By G. F. Rossi (auth.), Professor Jan Gybels, Professor Edward R. Hitchcock, Priv.-Doz. Christoph Ostertag, Professor Gian Franco Rossi, Professor Jean Siegfried, Professor Gabor Szikla (eds.)
Local interstitial radiation remedy of intrinsic and inaccessible mind tumors is faced with significant difficulties: 1. The tolerance of ordinary mind tissue, that's often serious about neighborhood tumor irradiation, i.e. perifocal white subject edema and demyelinating results, is important. 2. information on radiation results of implanted radioactive resources on neoplastic tissue, i.e. facts at the radiosensitivity and at the biology of tumors, are nonetheless largely unavailable. In medical perform the dose with which to accomplish a given quantity of tumor necrosis is approximately anticipated. This record offers with the experimental findings of Iodine-125 and Iridium-I92 everlasting implants in fit and neoplastic mind tissue. Our personal experimental findings are correlated with experimental facts on Yttnul11-l)O irradiation from the literature. The research is directed to gather info at the tolerance non-tumoral mind tissue and to try to set up a dose-response courting. Morphologic adjustments within the puppy mind Following Interstitial Iodine-125 Irradiation Iodine-I25 seeds (manufactured via three M corporation, St. Paul, M. N.) with an job of 3.55 mCi have been completely implanted lower than stereotactic stipulations into the subcortical white subject of the gyrus coronalis of the left hemisphere in 6 beagle canine. One animal with a non-radioactive seed implanted less than related operative stipulations served as a regulate. The animals have been allowed to outlive 25, forty six, seventy one, ninety four, 248, 368 days, respectively, after the implantation. The keep watch over animal survived forty six days. a close description of the experimental technique is given in other places sixteen. 17.
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Extra info for Advances in Stereotactic and Functional Neurosurgery 6: Proceedings of the 6th Meeting of the European Society for Stereotactic and Functional Neurosurgery, Rome 1983
Z. EEG-EMG 10 (1979), 62-69. 23. Wieser, H. , Electroc1inical Features of the Psychomotor Seizure, (242 pp. Stuttgart-New York-London: G. Fischer, Butterworths. 1983. 24. Zetterberg, L. , Spike detection by computer and by analog equipment. ), pp. 227-242. New York: Raven Press. 1973. Advances 6 3 Acta Neurochirurgica, Supp!. 33, 35-46 (1984) © by Springer-Verlag 1984 Changes of Energy Metabolism and Regional Cerebral Blood Flow Studied by Positron Emission Tomography in the Interietal Phase of Partial Epilepsy Y.
3 to 10 spontaneous seizures were analyzed in each patient. In addition, in some cases, seizures were provoked pharmacologically or by local brain electrical stimulations. The types of the phenomena observed as the first seizure manifestation were the following. a) Motor: i) tonic (9 cases), mainly adversive head rotation and postural limbs modifications; ipsilateral head turning in 2 cases; ii) clonic (3 cases); iii) complex gesture (2 cases). Loss of consciousness was associated with the i and iii types of motor events.
A different and more sophisticated application oflinear system analysis is based on the so called "partial coherences" and has been described by Gersch 9 and others in the last ten years. In this method triples of signals are considered. Computing partial coherences implies as a first step elimination from each of the 2 signals of a pair that part, that can be considered as being determined by a third signal. If the partial coherence between 2 of the signals partialized on the 3rd signal is very low in a frequency band of high spectral energy, and if only one of the 3 signals has this property, the third signal is considered to drive the 2 others.