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By Paul Singleton

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Dictionary of Microbiology & Molecular Biology

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But it remains attached (non-covalently) to the cell surface. ) aidB gene See ADAPTIVE RESPONSE. g. CANDIDIASIS of the lower respiratory tract; disseminated COCCIDIOIDOMYCOSIS; extrapulmonary CRYPTOCOCCOSIS; retinitis due to cytomegalovirus (BETAHERPESVIRINAE); herpes simplex oesophagitis; HIV-related encephalopathy; extrapulmonary HISTOPLASMOSIS; chronic infection with ISOSPORA; KAPOSI’S SARCOMA; primary lymphoma of the brain; extrapulmonary infection with Mycobacterium tuberculosis (see also MAC); pneumonia caused by PNEUMOCYSTIS CARINII; TOXOPLASMOSIS of the brain.

Alkane metabolism See HYDROCARBONS. alkB gene See ADAPTIVE RESPONSE. alkene metabolism See HYDROCARBONS. g. g. proteins and nucleic acids, substituting them with alkyl groups. g. g. NITROGEN MUSTARDS and MITOMYCIN C). g. on their reactivities, alkylating agents can be effective antimicrobial agents and/or MUTAGENS. g. alkyl-N-nitrosamines: see N-NITROSO COMPOUNDS) require prior metabolic activation (apparently to generate an alkyl carbonium cation). In general, methylating agents are more reactive with DNA than are the corresponding ethylating agents.

The linear dsDNA genome of HSV-1 (∼152 kbp) contains two regions, designated L (‘long’) and S (‘short’), each region flanked by inverted repeats; the ability of each region (L and S) to invert, independently, means that DNA isolated from virions will include four isomeric forms. The genome also includes several copies of a short sequence (a) – a cis-acting region involved in circularization of the genome. g. BOVINE ULCERATIVE MAMMILLITIS), and probably cercopithecine (or cercopithecid) herpesviruses 1 (B VIRUS) and 2.

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